You are here

Upper

Immunogenicity and bioanalysis

Classify and quantitate the complete patient immune response in a single test.

Lower
Applications
Dual-layer multiplexing

Multiple proteins, metabolites, subunits, oligonucleotides, etc.

Isotype of the antibody (Total IgG, IgA, IgM, IgE)

Subclass of the antibody (IgG1, IgG2, IgG3, IgG4)

Full Immunogenicity Profile – With Ig_plex’s unique dual-layer multiplexing capability, you are able to get a full immune response in one reaction. Measure multiple isotypes and immunoglobulin subclasses, and from multiple proteins if you like, in one well.

Epitope Mapping – Epitope mapping is becoming more and more important in measuring the safety and efficacy of therapeutics. Now, with Ig_plex, SQI can custom create a fully automated assay for you with individual epitope variants and sub-units, while quantitatively measuring the immune response to each component, all in one well.

Multiplex PK Assays – PK testing is one of the tools life science and pharma researchers use in their workflow every day. Now, you can multiplex various pharmacokinetic assays, either quantitatively or qualitatively, all in one well.

Traditional Bridging Assays – A mainstay of bioanalytical testing, traditional bridging format assays are a work horse for pharmaceutical research. Ig_plex technology can deliver these assays to you in an automated high throughput fashion, while providing superior drug tolerance and equivalent or better sensitivity than ECL or traditional ELISA.

Benefits

SQI Diagnostics will cut the redundancy and cost out of your program through the seamless application of dual-layer multiplexing™. Besides the ability to report multiple proteins, plus multiple immunoglobulin isotypes and subclasses simultaneously, the system allows you to test all those targets in one well.

This side-by-side analysis of therapeutic proteins, drug metabolites, subunits or oligonucleotides will ensure you’re working with truly on-target data. SQI Diagnostics also provides expert assay development support to get you up and running faster. Tests can be ready to go in weeks or even days.